1.

Fully automatic sample application, suitable for routine

Application of sample as spots, bands or rectangles

Application of sample solutions onto any planner medium

Application of sample volume - 0.1 to 5 microlitre by contact transfer

Application of sample volume - 0.5 to >50 microlitre by spray on technique

Facility for sequential application of the sample from different vials into the same position

Data input and processing through soft ware -PC controlled

All consumables/spares of Automatic TLC Sampler for smooth running the system for 5 years should be provided separately

2.

Development chamber

All glass, small internal volume chambers, bottom divided into two parts, maximum 5-15 ml mobile phase with all ss lid. Chamber sizes- 20 x 20cm (4 nos), 20x10cm (1 no), 10 x 10 cm (2 nos) for plates

Horizontal developing chamber for 20 x 10 cm and 10 x 10 cm plates

3.

Software controlled gradient elution system

Minimum five or more solvent system should accommodate simultaneously for elution in gradient mode

Gradient and developing distance for each run should be monitored through software

Resolution for gradient elution system should be as peak width 1 mm.

Data input and processing through soft ware -PC controlled

All consumables/spares of Gradient Automatic multiple development chamber for smooth running the system for 5 years should be provided separately

4.

Chromatography visualization/ derivatisation system

UV cabinet with duel wave length 254 nm and 366 nm,( 4nos)

Visible light protection for viewers eye, skin with good illumination. Auto switch off after 10 min.

Dipping chamber for post chromatography derivatisation and uniform derivatisation for quantitation.

5.

Photodocumentation system

High resolution 12 bit CCD camera and system software controlled.

Auto image optimization

Digital image evaluation

Proper storage of the image and analysis of the image with printable format in colour laserjet printer

6.

Measurement modes - reflection, absorbance, fluorescence, transmission

Automatic selection of measurement modes

Object formats upto 200 x 200 mm

Spectral range 190 to 800 nm

Automatic start of all lamps like deuterium, halogen-tungsten, high pressure mercury lamp

Data step resolution- minimum 25 m m

Scanning speed 1-100 mm/s

Spectrum recording up to 100 nm/s

All consumables/spares of Densitometric scanner for smooth running the system for 5 years should be provided separately

7.

Data evaluation of Densitometer system

Software should controlled the scanner and processes data as-

Built in self diagonostic

Easy graphic , automatic recording of spectra, multiple wavelength scan, colour plots of data

Automatic video integration, auto baseline correction, spot check facility, 3D display with data storage

Quantitative evaluation - Calibration- single level, multilevel with linear or non-linear regression using internal or external standards. Statistical evaluation of the data

Sub-component evaluation, impurities calculation as per US or European pharmacopoeias

Track optimization

Spectrum library creation, library spectra search

Lamp life evaluation

Validation qualification, GLP or GMP compliance

Software should be latest version and future upgradable free of cost.

8.

Temp range 25-200 0C

9.

Automatic TLC Sprayer

Pheumatic cordless, using rechargeable batteries, spray heads, bottles of 50 ml attachable - two nos.

Glass reagent sprayer with spray head and 100 ml flask - four nos.

10.

TLC Spray cabinet –Two numbres

Complete with PVC made, with blower, and exhaust house

11.

Consumables Pre-coated HPTLC (MERCK) plates

HPTLC plates silica gel 60 F 254 , 200 m m, 10 x 10 cm, 25 per pack- 3 packs

HPTLC plates silica gel 60 F 254 , 200 m m, 20 x 10 cm, 50 per pack- 5 packs

HPTLC aluminium sheets silica gel 60 F 254 , 200 m m, 20 x 20 cm, 25 per pack- 3 packs

TLC plates silica gel 60 F 254 , 250 m m, 20 x 20 cm, 25 per pack- 5 packs

HPTLC plates silica gel 60 F 254 , 250 m m, 5 x 5 cm, 25 per pack- 3 packs

12

Require data station (PC) Latest version, colour laser printer, TFT Monitor 17’’ should be supplied [ Dell / IBM make and supply by HPTLC manufacturer.

13.

TLC Plate box- Two

14.

Test dye Mixtures for functional checks

15.

2 years warranty of the full system should be provided

16.

ISO 9001/GLP/GMP/CE/CFR compliance

17.

All specification should be supported by printer literature of the manufacturer only

18.

Two scientist should be trained in analysis of the crime exhibits

19.

AMC charges should be mentioned for al least three years after warranty period.